Therapeutic Asset Ratings

461 results matching 1 filter

129,767 assets · 8,707 sponsors · 3,128 indications

Methodology v0.2

Asset	Sponsor	Phase	Rating
Lorlatanib Non-Small Cell Lung Carcinoma	Pfizer	P3	CCC (52)
Lorlatanib Neoplasm	Pfizer	P3	CCC (52)
PEGASPARGASE Lung Cancer	Pfizer	P3	CCC (52)
pf-08634404 Lung Cancer	Pfizer	P3	CCC (52)
Vepdegestrant Breast Neoplasm	Pfizer	P2	CCC (52)
PF-06939926 IS A RECOMBINANT AAV VECTOR CONTAINING THE AAV SEROTYPE 9 (AAV9) CAPSID PACKAGING A MINIATURIZED CODON-OPTIMIZED VERSION OF THE DMD GENE(CALLED OPTI-DYS.DELTA.3978) WHICH ENCODES THE DOMAINS MINIMALLY REQUIRED FOR FUNCTIONALITY OF THE DYSTROPHIN PROTEIN (MINI-DYSTROPHIN). A SYNTHETIC POLYADENYLATION (SPOLYA) SEQUENCE FOLLOWS THE OPTI-DYS.DELTA.3978 GENE. CARDIAC AND SKELETAL MUSCLE-SPECIFIC TRANSGENE EXPRESSION IS MEDIATED BY A SYNTHETIC ENHANCER AND PROMOTER. THE EXPRESSION CONSTRUCT IS FLANKED BY THE AAV2 INVERTED TERMINAL REPEATS (ITRS). THE 3978 BASEPAIR MINI-DYSTROPHIN OPEN READING FRAME ENCODES THE N-TERMINUSHINGE REGIONS H1, H3 AND H4SPECTRIN-LIKE REPEATS R1, R2 AND R22-24AND THE C-TERMINAL CYSTEINE-RICH REGION OF THE DYSTROPHIN PROTEIN. Duchenne Muscular Dystrophy	Pfizer	P3	CCC (51)
Calaspargase Pegol Lung Neoplasms	Pfizer	P2	CCC (51)
Cytosin-Arabinosid Lung Neoplasms	Pfizer	P2	CCC (51)
Daunorubicin Lung Neoplasms	Pfizer	P2	CCC (51)
FULVESTRANT Head And Neck Cancer	Pfizer	P2	CCC (51)
Letrozole Head And Neck Cancer	Pfizer	P2	CCC (51)
Maplirpacept Diffuse Large B-Cell Lymphoma	Pfizer	P2	CCC (51)
PEGASPARGASE Lung Neoplasms	Pfizer	P2	CCC (51)
pf-08634404 Lung Neoplasm	Pfizer	P2	CCC (51)
PREDNISONE TABLETS Lung Neoplasms	Pfizer	P2	CCC (51)
(+)-VINCRISTINE Lung Neoplasms	Pfizer	P2	CCC (51)
Cmp 001 Ovarian Cancer	Pfizer	P3	CCC (50)
Ivuxolimab Ovarian Cancer	Pfizer	P3	CCC (50)
Lorlatanib Ovarian Cancer	Pfizer	P3	CCC (50)
PF-07850327 Breast Cancer	Pfizer	P3	CCC (50)
PF-07104091 Breast Cancer	Pfizer	P2	CCC (50)
pf-07976016 Obesity Disorder	Pfizer	P2	CCC (50)
Inclacumab Vaso-occlusive Crisis	Pfizer	P3	CCC (49)
Letrozole Sickle Cell Disease	Pfizer	P1	CCC (49)
(+)-VINCRISTINE Pancreatic Ductal Adenocarcinoma	Pfizer	P1/2	CCC (49)

Showing 226 to 250 of 461 assets

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