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Therapeutic Asset Ratings

7,018 results matching 1 filter

129,767 assets · 8,707 sponsors · 3,128 indications
Methodology v0.2
AssetSponsorPhaseRating
Vinorelbine
Aggressive Non-Hodgkin Lymphoma
Institute of Hematology & Blood Diseases Hospital, ChinaP3BB (70)
Vinorelbine
Lung Large Cell Carcinoma
AIO-Studien-gGmbHP3BB (70)
Xzp-3621
Non-Small Cell Lung Carcinoma
Xuanzhu Biopharmaceutical Co., Ltd.P3BB (70)
Zipalertinib
Non-Small Cell Lung Carcinoma
Jonsson Comprehensive Cancer CenterP3BB (70)
Zofran
Chronic Lymphocytic Leucemia
Mayo ClinicP3BB (70)
Zongertinib
Non-Small Cell Lung Carcinoma
Boehringer IngelheimP3BB (70)
4,5,7,4',5',7'-HEXAHYDROXY-2,2'-DIMETHYLNAPHTHODIANTHRONE
Primary Cutaneous T-Cell Non-Hodgkin Lymphoma
SoligenixP3BB (69)
Acetylsalicylic Acid
Breast Carcinoma
Mayo ClinicP3BB (69)
Acetylsalicylic Acid
Lynch Syndrome
M.D. Anderson Cancer CenterP3BB (69)
ARG
Sickle Cell Disease
Tanta UniversityP3BB (69)
Autologous CD34+ cells isolated from mobilised peripheral blood by positive selection, modified by CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9) mediated gene editing consisting of a guide RNA (gRNA) introduced transiently as ribonucleoprotein (RNP) complex, targeting the erythroid lineage-specific enhancer region of BCL11A (B-cell lymphoma/leukemia 11A). The site-specific cleavage by Cas9 forms a double strand break (DSB), which is subsequently repaired by nonhomologous end-joining (NHEJ), leading to the transcriptional repression of BCL11A, a repressor of ?-globin gene transcription
Disease Of Genetic Or Genomic Mechanism
Vertex Pharmaceuticals IncorporatedP3BB (69)
Axitinib
Kidney Neoplasm
PfizerP3BB (69)
Benzeneethanamine, N-ethyl-?-methyl-4-(trifluoromethyl)-, hydrochloride, (±)-
Lennox-Gastaut Syndrome
University of ChicagoP3BB (69)
Calcium folinate pentahydrate
Acute Lymphoblastic Leukemia
Andrew E. Place, MDP3BB (69)
Calcium folinate pentahydrate
B Acute Lymphoblastic Leukemia
SWOG Cancer Research NetworkP3BB (69)
Calcium folinate pentahydrate
Colon Cancer
AkesoP3BB (69)
Calcium folinate pentahydrate
Lymphoma
Juno Therapeutics, Inc., a Bristol-Myers Squibb CompanyP3BB (69)
Calcium folinate pentahydrate
Metastatic Cancer
I-Mab Biopharma US LimitedP3BB (69)
Calcium folinate pentahydrate
Metastatic Malignant Neoplasm in the Peritoneum
City of Hope Medical CenterP3BB (69)
Calcium folinate pentahydrate
Rectal Adenocarcinoma
Sixth Affiliated Hospital, Sun Yat-sen UniversityP3BB (69)
Capecitabine
Gastroesophageal Junction Adenocarcinoma
I-Mab Biopharma US LimitedP3BB (69)
Capecitabine
Metastatic Neoplasm
University of Southern CaliforniaP3BB (69)
Carboplatin
Adenosquamous Lung Carcinoma
NRG OncologyP3BB (69)
Casodex
Prostate Adenocarcinoma
OHSU Knight Cancer InstituteP3BB (69)
cc-5013
B-Cell Chronic Lymphocytic Leukemia
Vitebsk Regional Clinical Cancer CentreP3BB (69)
Showing 626 to 650 of 7,018 assets
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