Therapeutic Asset Ratings

6,308 results matching 1 filter

91,583 assets · 7,906 sponsors · 3,128 indications

Methodology v0.2

Asset	Sponsor	Phase	Rating
Atezolizumab Acute Myeloid Leukemia With Multilineage Dysplasia	University of Southern California	P1/2	CCC (48)
Atezolizumab Chordoma	National Cancer Institute (NCI)	P1/2	CCC (48)
Atezolizumab Rhabdoid Tumor	National Cancer Institute (NCI)	P1/2	CCC (48)
Atezolizumab Thyroid Cancer	TransThera Sciences (Nanjing), Inc.	P1/2	CCC (48)
Atezolizumab Urinary Bladder Neoplasm	Cancer Research UK	P1/2	CCC (48)
ATORVASTATIN Thyroid Gland Papillary Carcinoma	Cancer Institute and Hospital, Chinese Academy of Medical Sciences	P1/2	CCC (48)
Autologous Cd19-Directed Chimeric Antigen Receptor T-Cells Adult Acute Lymphoblastic Leukemia	University of Alberta	P1/2	CCC (48)
Autologous Cd19-Directed Chimeric Antigen Receptor T-Cells Non-Hodgkin Lymphoma	University of Alberta	P1/2	CCC (48)
Autologous Cd19-Directed Chimeric Antigen Receptor T-Cells Childhood Acute Lymphoblastic Leukemia	University of Alberta	P1/2	CCC (48)
Autologous Cd34+ Cells Transduced With A Lentiviral Vector Containing The Human Sgsh Gene Mucopolysaccharidosis Type 3A	University of Manchester	P1/2	CCC (48)
Autologous Cd34+ Cells Transduced With Tns9.3.55 Mucopolysaccharidosis Type 2	University of Manchester	P1/2	CCC (48)
Autologous Cd34+ Cells Transduced With Tns9.3.55 Mucopolysaccharidosis Type 3A	University of Manchester	P1/2	CCC (48)
Autologous Cd34+ Hscs Transduced Ex Vivo With Cd11B Lv Encoding Human Ids Tagged With Apoeii Mucopolysaccharidosis Type 2	University of Manchester	P1/2	CCC (48)
Autologous Dual-Target Car-T Cells Selected From The Predefined Target Library. Refractory Malignant Neoplasm	Beijing Biotech	P1/2	CCC (48)
Autologous human CD34+ hematopoietic stem/precursor cells (HSPCs), obtained from peripheral blood by leukapheresis from plerixaformobilized sickle cell disease (SCD) patients or granulocyte colony stimulating factor (G-CSF) and plerixafor-mobilized transfusion dependent betathalassemia (TDT) patients, genetically modified ex vivo by CRISPR/Cas12a (clustered regularly interspaced palindromic repeats/modified Acidaminococcus sp. Cas12a) endonuclease complexed with a guide RNA (gRNA) that targets the CCAAT-box region of both gamma globin gene (HBG1 and HGB2) promoters on chromosome 11, creating indels that disrupt repressor binding and increase gamma globin expression. The editing components are introduced into the target cell population as a ribonucleoprotein complex by electroporation. The cell suspension is enriched for CD34+ cells using magnetic bead separation. Following electroporation, the cells are cultured in media containing thrombopoietin, Fms-related tyrosine kinase 3 ligand (Flt3L), and stem cell factor (SCF). The substance consists of cells with ?70% CD34/CD45+ purity and ?70% on-target editing. Beta-Thalassemia Major	Editas Medicine, Inc.	P1/2	CCC (48)
Autologous Immune Cells Lung Cancer	Liaoning Medical Diagnosis and Treatment Technology Research and Development Co., Ltd.	P1/2	CCC (48)
Autologous Natural Killer Cell-Like Ctls Fallopian Tube Cancer	Roswell Park Cancer Institute	P1/2	CCC (48)
Autologous Natural Killer Cell-Like Ctls Ovarian Cancer	Roswell Park Cancer Institute	P1/2	CCC (48)
Autologous Natural Killer Cell-Like Ctls Fallopian Tube Carcinoma	Roswell Park Cancer Institute	P1/2	CCC (48)
Autologous Natural Killer Cell-Like Ctls Ovarian Carcinoma	Roswell Park Cancer Institute	P1/2	CCC (48)
Autologous Natural Killer Cell-Like Ctls Primary Peritoneal Carcinoma	Roswell Park Cancer Institute	P1/2	CCC (48)
AUTOLOGOUS RAPAMYCIN-RESISTANT TH1/TC1 CELLS RAPA-201 Lung Cancer	Rapa Therapeutics LLC	P1/2	CCC (48)
AUTOLOGOUS RAPAMYCIN-RESISTANT TH1/TC1 CELLS RAPA-201 Laryngeal Squamous Cell Carcinoma	Rapa Therapeutics LLC	P1/2	CCC (48)
AUTOLOGOUS RAPAMYCIN-RESISTANT TH1/TC1 CELLS RAPA-201 Nasopharyngeal Squamous Cell Carcinoma	Rapa Therapeutics LLC	P1/2	CCC (48)
AUTOLOGOUS RAPAMYCIN-RESISTANT TH1/TC1 CELLS RAPA-201 Oral Cavity Squamous Cell Carcinoma	Rapa Therapeutics LLC	P1/2	CCC (48)

Showing 801 to 825 of 6,308 assets

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