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2,4-PYRIMIDINEDIAMINE, N(SUP 4)-(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)-N(SUP 2)-((3-(1-METHYLETHYL)-5-ISOXAZOLYL)METHYL)-6-(4-METHYL-1-PIPERAZINYL)-

Chronic Myeloid Leukemia

ExelixisSmall moleculePhase 1Dormant
CC
41/ 100
Provisional rating · Methodology v0.2

Rating breakdown

Clinical Evidence
28/ 100
Competitive Position
81/ 100

Competitive context

86 Active assets in the Chronic Myeloid Leukemia cohort.

Asset / SponsorPhaseRating
Cyclophosphamide
City of Hope Medical Center
Phase 3BBB
Nilotinib
Novartis Pharmaceuticals
Phase 4BBB
Fludarabine
Fred Hutchinson Cancer Center
Phase 3BBB
Therapeutic Allogeneic Lymphocytes
University of Chicago
Phase 2BBB
Romidepsin
Center for International Blood and Marrow Transplant Research
Phase 2BBB

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Same molecule, other indications

2,4-PYRIMIDINEDIAMINE, N(SUP 4)-(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)-N(SUP 2)-((3-(1-METHYLETHYL)-5-ISOXAZOLYL)METHYL)-6-(4-METHYL-1-PIPERAZINYL)- is also rated in:

B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)Dormant
CC
Indicative ·
41 / 100
View asset →
cancerDormant
C
Indicative ·
37 / 100
View asset →
lymphomaDormant
C
Indicative ·
37 / 100
View asset →

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