Floatz Rating
CCC53/100
Confidence
Indicative
Sponsor
MacroGenics
Modality
Small molecule
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT05551117CT.gov A Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumors | — | Terminated | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Moderate confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Anus Neoplasm
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Abiraterone (this asset) | MacroGenics | P2 | CCC · 53 |
| Fluorouracilum | Jessa Hospital | P4 | BB |
| v503 | Merck Sharp & Dohme LLC | P3 | BB |
| Mitomycins | Blokhin's Russian Cancer Research Center | P3 | B |
| Capecitabine | Blokhin's Russian Cancer Research Center | P3 | B |
| Aijp (Arnebia Indigo Jade Pearl) | University of California, San Francisco | P2 | B |
| Vgx-3100 | Inovio Pharmaceuticals | P2 | B |
| 18f-flt | John M. Buatti | P2 | CCC |
| Enzalutamide | MacroGenics | P2 | CCC |
+4 more in the Anus Neoplasm cohort
Other indications for Abiraterone
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Prostate Carcinoma | — | P4 | BBB · 72 |
| Prostate Neoplasm | — | P3 | BB · 71 |
| Metastatic Prostate Carcinoma | — | P4 | BB · 70 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Abiraterone in Anus Neoplasm. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/abiraterone-anus-neoplasm
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