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Adriamycin

Hepatoblastoma

Floatz Rating
B60/100
Confidence
Indicative
v0.2
Sponsor
Children's Oncology Group
Modality
Small molecule
Development Phase
Phase 3
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
45Indicative
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery
Active Not Recruiting
Paediatric Hepatic International Tumour Trial
Active Not Recruiting

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Moderate confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Hepatoblastoma

AssetSponsorPhaseRating
Adriamycin (this asset)Children's Oncology GroupP3B · 60
EtoposideChildren's Oncology GroupP3BB
CyclophosphamideSt. Jude Children's Research HospitalP2BB
OxaliplatinChildren's Oncology GroupP3BB
(+)-VincristineUniversity of BirminghamP3BB
CarboplatinChildren's Oncology GroupP3BB
Gm-CsfXinhua Hospital, Shanghai Jiao Tong University School of MedicineP4B
FluorouracilumChildren's Oncology GroupP3B
Vincristine SulfateChildren's Oncology GroupP3B

+42 more in the Hepatoblastoma cohort

Other indications for Adriamycin

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Citation

Floatz Terminal. Adriamycin in Hepatoblastoma. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 13, 2026.
https://terminal.floatz.ai/assets/adriamycin-hepatoblastoma

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