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Allogeneic Cd123Car-Cd28-Cd3Zeta-Egfrt-Expressing T-Lymphocytes

Interleukin-3 Receptor Subunit Alpha Positive

City of Hope Medical CenterCell therapyPhase 1Active
CC
43/ 100
Provisional rating · Methodology v0.2

Rating breakdown

Clinical Evidence
28/ 100
Competitive Position
95/ 100

Competitive context

3 Active assets in the Interleukin-3 Receptor Subunit Alpha Positive cohort.

Asset / SponsorPhaseRating
HUMANIZED, DUAL-AFFINITY RE-TARGETING, OR (DART), MOLECULE THAT RECOGNIZES BOTH CD123 AND CD3
City of Hope Medical Center
Phase 2CCC
Autologous Cd123Car-Cd28-Cd3Zeta-Egfrt-Expressing T Lymphocytes
City of Hope Medical Center
Phase 1CC
Cyclophosphamide
City of Hope Medical Center
Phase 1CC
Fludarabine
City of Hope Medical Center
Phase 1CC

Same molecule, other indications

Allogeneic Cd123Car-Cd28-Cd3Zeta-Egfrt-Expressing T-Lymphocytes is also rated in:

acute biphenotypic leukemiaDormant
CC
Indicative ·
43 / 100
View asset →
CD4+/CD56+ hematodermic neoplasmDormant
CC
Indicative ·
43 / 100
View asset →
adult acute lymphoblastic leukemiaDormant
CC
Indicative ·
43 / 100
View asset →

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