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AN ADENOVIRUS VECTOR CANCER VACCINE COMPOSED OF A REPLICATION-DEFECTIVE, SER OTYPE 5 ADENOVIRUS (AD5) THAT HAS BEEN MODIFIED BY REMOVAL OF THE E1, E2B AND E3 GENES AND INSERTION OF A MODIFIED HUMAN MUCIN 1 GENE ENCODING AGONIST EPITOPES DESIGNED TO INCREASE CYTOTOXIC T LYMPHOCYTE ANTITUMOR IMMUNE RESPONSES

Metastatic Pancreatic Cancer

ImmunityBio, Inc.vaccinePhase 2Dormant
C
36/ 100
Provisional rating · Methodology v0.2

Rating breakdown

Clinical Evidence
21/ 100
Competitive Position
73/ 100

Competitive context

330 Active assets in the Metastatic Pancreatic Cancer cohort.

Asset / SponsorPhaseRating
IMMUNOGLOBULIN G1, ANTI-(HUMANIZED MOUSE MONOCLONAL HR3 .BETA.1 CHAIN ANTI-HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR), DISULFIDE WITH HUMANIZED MOUSE MONOCLONAL HR3 .KAPPA.-CHAIN, DIMER
Chinese PLA General Hospital
Phase 4BBB
Metformin
State University of New York - Downstate Medical Center
Phase 2BBB
FLUOROURACILUM
Jonsson Comprehensive Cancer Center
Phase 4BBB
S-1
Liu Xiufeng
Phase 4BB
Eloxatin
Jonsson Comprehensive Cancer Center
Phase 4BB

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Same molecule, other indications

AN ADENOVIRUS VECTOR CANCER VACCINE COMPOSED OF A REPLICATION-DEFECTIVE, SER OTYPE 5 ADENOVIRUS (AD5) THAT HAS BEEN MODIFIED BY REMOVAL OF THE E1, E2B AND E3 GENES AND INSERTION OF A MODIFIED HUMAN MUCIN 1 GENE ENCODING AGONIST EPITOPES DESIGNED TO INCREASE CYTOTOXIC T LYMPHOCYTE ANTITUMOR IMMUNE RESPONSES is also rated in:

non-small cell lung carcinomaDormant
CC
Indicative ·
40 / 100
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triple-negative breast carcinomaDormant
CC
Indicative ·
40 / 100
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hepatocellular carcinomaDormant
C
Indicative ·
33 / 100
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