Aspirin
Ischemic Stroke
Floatz Rating
BB71/100
Confidence
Indicative
Sponsor
Nanfang Hospital, Southern Medical University
Modality
Small molecule
Development Phase
Phase 4 / Approved
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
75High confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT07604298CT.gov Efficacy and Safety of Indobufen, Aspirin, Cilostazol and Clopidogrel in the Treatment of Ischemic Stroke | — | Not Yet Recruiting | — | — | — |
NCT07617870CT.gov Pro-urokinase for Extended-Window Posterior Circulation Stroke | — | Not Yet Recruiting | — | — | — |
NCT07468448CT.gov Combination Antithrombotic Treatment for Prevention of Recurrent Ischemic Stroke in IntraCranial Atherosclerotic diseaSe (CATIS- ICAS) | — | Not Yet Recruiting | — | — | — |
NCT07540416CT.gov Tenecteplase for Late-Window Stroke Guided by DWI-FLAIR Mismatch | — | Not Yet Recruiting | — | — | — |
NCT07519889CT.gov Observational Study to Assess the Safety of rhTNK-tPA (Mingfule®) vs. Rt-PA (Actilyse®) in Treating Acute Ischemic Stroke | — | Not Yet Recruiting | — | — | — |
NCT07454707CT.gov Testing a New Treatment Strategy to Improve Secondary Stroke Prevention for Older Adults: The STROKE75+ Trial | — | Not Yet Recruiting | — | — | — |
NCT05225961CT.gov ATILA Project: Aspirin Versus Tirofiban in Endovascular Treatment for Patients With Acute Ischemic Stroke Due to Tandem Lesion | — | Completed | — | — | — |
NCT07347626CT.gov Eptifibatide for Extended Window Ischemic Stroke After Thrombolysis | — | Not Yet Recruiting | — | — | — |
NCT07335107CT.gov Intravenous Tirofiban After Bridging Therapy for Acute Stroke With Atherosclerotic Large Artery Occlusion | — | Not Yet Recruiting | — | — | — |
NCT07275749CT.gov Acetyl-leucine in Post-stroke Ataxia | — | Recruiting | — | — | — |
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NCT07237308CT.gov BEACON-AA: Apixaban With or Without Clopidogrel in Stroke Patients With Atrial Fibrillation and Cerebral Atherosclerosis | — | Not Yet Recruiting | — | — | — |
NCT07201688CT.gov Phase III Clinical Trial of rhTNK-tPA in Treating Acute Ischemic Stroke With Extended Time Window. | — | Recruiting | — | — | — |
NCT06414499CT.gov Teneteplase Reperfusion Therapy in Acute Ischemic Cerebrovascular Events-Ⅳ | — | Recruiting | — | — | — |
NCT06486792CT.gov Stroke Prevention In Ischemic Stroke With Covert Atrial Fibrillation | — | Recruiting | — | — | — |
NCT06853535CT.gov Precision Antiplatelet Therapy Guided by Platelet Aggregation Function in Patients With Acute Ischemic STROKE | — | Recruiting | — | — | — |
NCT06601127CT.gov Study of Tiprogrel in the Treatment of High-risk Patients with Acute Ischemic Cerebrovascular Events (THRIVE). | — | Recruiting | — | — | — |
NCT06712004CT.gov A Dose-Response Controlled Trial of Bevifibatide for Acute Ischemic Stroke | — | Recruiting | — | — | — |
NCT06715007CT.gov Antiplatelet Therapy and Endothelial-stabilizing Agents in Cerebral Small Vessel Diseases | — | Recruiting | — | — | — |
NCT06587347CT.gov Tirofiban for the Prevention of Early Neurological Deterioration After Intravenous Thrombolysis in Acute Ischemic Stroke | — | Not Yet Recruiting | — | — | — |
NCT06584812CT.gov Study to Assess Pharmacokinetics, Pharmacodynamics and Safety of Tiprogrel in Healthy Subjects | — | Completed | — | — | — |
NCT06591338CT.gov Combining Aspirin With Ticagrelor or Clopidogrel in Large-vessel Minor Stroke or TIA | — | Recruiting | — | — | — |
NCT06591377CT.gov Combining Aspirin With Ticagrelor or Cilostazol in Large-vessel Minor Stroke or TIA | — | Recruiting | — | — | — |
NCT06243133CT.gov Pair Antiplatelet THerapy in Ischemic Stroke With Intracranial Artery Stenosis | — | Not Yet Recruiting | — | — | — |
NCT05604638CT.gov Early Administration of Tirofiban in Patients Treated With Tenecteplase for Acute Ischemic Stroke | — | Recruiting | — | — | — |
NCT06316570CT.gov Ticagrelor With Aspirin Dual Antiplatelet Therapy Combined With Intravenous Thrombolysis for Ischemic Stroke | — | Completed | — | — | — |
NCT06653348CT.gov Ticagrelor Based De-Escalation of Dual Antiplatelet Therapy in Ischemic Stroke | — | Recruiting | — | — | — |
NCT06541691CT.gov Coated or Chewable Aspirin and a Hybrid Strategy to Mitigate Adverse Effects of Air Pollution in Stable Atherosclerotic Disease | — | Recruiting | — | — | — |
NCT05700266CT.gov Anticoagulation Using Rivaroxaban on Top of Aspirin in Intracranial Atherosclerotic Stenosis | — | Unknown | — | — | — |
NCT06053021CT.gov Antiplatelet Therapy for AIS Patients With Thrombocytopenia | — | Unknown | — | — | — |
NCT05387954CT.gov PFO Closure, Oral Anticoagulants or Antiplatelet Therapy After PFO-associated Stroke in Patients Aged 60 to 80 Years | — | Recruiting | — | — | — |
NCT05752916CT.gov Intravenous Thrombolysis With rhTNK-tPA for Acute Non-large Vessel Occlusion in Extended Time Window | — | Completed | — | — | — |
NCT05476991CT.gov Evaluation of Low Dose Colchicine and Ticagrelor in Prevention of Ischemic Stroke in Patients With Stroke Due to Atherosclerosis | — | Recruiting | — | — | — |
NCT04818944CT.gov Clinical Trial to Evaluate the Safety of Continuous IV Tirofiban in Acute Ischemic Stroke | — | Withdrawn | — | — | — |
NCT06269432CT.gov Precise Antiplatelet THerapy Guided by Platelet Aggregation Function in Ischemic STROKE（PATH-STROKE） | — | Completed | — | — | — |
NCT05445895CT.gov A Study to Evaluate the Efficacy and Safety of Renexin CR in Patients With Acute Non-cardioembolic Ischemic Stroke | — | Completed | — | — | — |
NCT05193071CT.gov Early Antiplatelet for Minor Stroke Following Thrombolysis (EAST) | — | Completed | — | — | — |
NCT04733742CT.gov Endovascular Treatment With Versus Without Intravenous rhTNK-tPA in Stroke | — | Completed | — | — | — |
NCT06591312CT.gov Combining Aspirin With Ticagrelor or Clopidogrel in Minor Stroke or TIA | — | Recruiting | — | — | — |
NCT06591351CT.gov Combining Aspirin With Cilostazol or Clopidogrel in Large-vessel Minor Stroke or TIA | — | Recruiting | — | — | — |
NCT04588337CT.gov INtravenous TNK for Acute isChemicsTroke in China | — | Completed | — | — | — |
NCT06120725CT.gov Ticagrelor Versus Clopidogrel in Large Vessel Ischemic Stroke | — | Completed | — | — | — |
NCT04797013CT.gov Tenecteplase Reperfusion Therapy in Acute Ischemic Cerebrovascular Events-Ⅱ | — | Completed | — | — | — |
NCT04809818CT.gov A Study to Evaluate Safety and PK of Multiple Doses of LT3001 Drug Product and Drug-drug Interaction in Healthy Subjects | — | Completed | — | — | — |
NCT04847752CT.gov Study of Predictive Factors Related to Prognosis of Patients With Ischemic Stroke Due to Large-artery Atherosclerosis | — | Recruiting | — | — | — |
NCT05476081CT.gov A REAl-life Study on Short-term DAPT in Patients With Ischemic Stroke or TIA | — | Completed | — | — | — |
NCT05531942CT.gov Antiplatelet Effect of Ginkgo Diterpene Lactone Meglumine Injection in Acute Ischemic Stroke | — | Unknown | — | — | — |
NCT05663307CT.gov The Effect of Ginkgolide on Clinical Improvement of Patients With Acute Ischemic Stroke | — | Unknown | — | — | — |
NCT04504864CT.gov Low-dose Aspirin Therapy in Patients With Ischemic Stroke and Microbleeds | — | Unknown | — | — | — |
NCT04425590CT.gov The Benefit of Add On DLBS1033 for Ischemic Stroke Patient | — | Unknown | — | — | — |
NCT04142125CT.gov Combination Antithrombotic Treatment for Prevention of Recurrent Ischemic Stroke in Intracranial Atherosclerotic Disease | — | Completed | — | — | — |
NCT03961334CT.gov MidregiOnal Proatrial Natriuretic Peptide to Guide SEcondary Stroke Prevention | — | Unknown | — | — | — |
NCT04142151CT.gov Double Randomized and Placebo Controlled Trail of Sanchitongshu Combined Antiplatelet Drug to Prevent Ischemic Stroke | — | Unknown | — | — | — |
NCT04330872CT.gov An Investigation Into The Impact Of Enteric Coated Of Aspirin In Patients With Newly Diagnosed Ischemic Stroke. | — | Completed | — | — | — |
NCT06522113CT.gov Cilostazol and Aspirin in Stroke and TIA | — | Completed | — | — | — |
NCT03871517CT.gov INdobufen Versus aSpirin in acUte Ischemic stRokE,INSURE | — | Completed | — | — | — |
NCT03766581CT.gov A Study on BMS-986177 for the Prevention of a Stroke in Patients Receiving Aspirin and Clopidogrel | — | Completed | — | — | — |
NCT03649711CT.gov Chronic Kidney Disease (CKD) Platelet Study | — | Completed | — | — | — |
NCT03578822CT.gov Thrombolysis With rhPro-UK in 4.5-6 Hours After Acute Ischemic Stroke in a Double-blinded,Controlled Trial | — | Completed | — | — | — |
NCT03552354CT.gov Argatroban Combined With Antiplatelet Versus Antiplatelet for Acute Ischemic Stroke | — | Completed | — | — | — |
NCT03219645CT.gov Ginkgo Diterpene Lactone Meglumine Injection on Platelet Reactivity in Acute Ischemic Stroke | — | Unknown | — | — | — |
NCT05512546CT.gov The Prevention of Thromboembolic Complications Associated With Coil Embolization | — | Completed | — | — | — |
NCT02983214CT.gov Diabetic Artery Obstruction: is it Possible to Reduce Ischemic Events With Cilostazol? | — | Completed | — | — | — |
NCT02526225CT.gov A Safety and Effective Study of Ginkgolides Diterpene Lactone Meglumine Injection in the Treatment of Ischemic Stroke. | — | Completed | — | — | — |
NCT02133521CT.gov DLBS1033 for Acute Ischemic Stroke Patients | — | Terminated | — | — | — |
NCT02362984CT.gov DLBS1033 for the Treatment of Acute Ischemic Stroke | — | Terminated | — | — | — |
NCT02181361CT.gov Hirudin Plus Aspirin in the Secondary Prevention of Cardioembolic Stroke Due to Nonvalvular Atrial Fibrillation | — | Completed | — | — | — |
NCT01994720CT.gov [SOCRATES -Acute Stroke Or Transient IsChaemic Attack TReated With Aspirin or Ticagrelor and Patient OutcomES] | — | Completed | — | — | — |
NCT01924325CT.gov Apixaban Versus Dual-antiplatelet Therapy (Clopidogrel and Aspirin) in Acute Non-disabling Cerebrovascular Events | — | Unknown | — | — | — |
NCT03431909CT.gov Evaluation Of HUK in Acute Stroke Patients: MRS and CTP | — | Completed | — | — | — |
NCT02071004CT.gov DS1040b/Aspirin Drug/Drug Interaction Study | — | Completed | — | — | — |
NCT01762163CT.gov Efficacy and Safety of Qizhitongluo Capsule in the Recovery Phase of Ischemic Stroke | — | Completed | — | — | — |
NCT01923818CT.gov Treatment of Rivaroxaban Versus Aspirin for Non-disabling Cerebrovascular Events | — | Unknown | — | — | — |
NCT01800357CT.gov Efficacy and Safety of Mildronate for Acute Ischemic Stroke | — | Unknown | — | — | — |
NCT01763606CT.gov Enoxaparin Versus Aspirin in Patients With Cancer and Stroke | — | Completed | — | — | — |
NCT01675115CT.gov Efficacy of BNG-1 to Treat Acute Ischemic Stroke | — | Completed | — | — | — |
NCT01790997CT.gov Efficacy of DLBS1033 in Patients With Acute Ischemic Stroke | — | Completed | — | — | — |
NCT03116269CT.gov The Effect of Cilostazol Compared to Aspirin on Endothelial Function in Acute Cerebral Ischemia Patients | — | Completed | — | — | — |
NCT00966316CT.gov Establishment and Evaluation to the Effects of a Clinical Pathway for Acute Ischemic Stroke | — | Completed | — | — | — |
NCT01831011CT.gov Mildronate for Acute Ischemic Stroke | — | Completed | — | — | — |
NCT00061373CT.gov Combination Anti-Platelet and Anti-Coagulation Treatment After Lysis of Ischemic Stroke Trial (CATALIST) | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
65High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Ischemic Stroke
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Aspirin (this asset) | Nanfang Hospital, Southern Medical University | Approved | BB · 71 |
| Ticagrelor | Sichuan Provincial People's Hospital | P4 | BBB |
| Cilostazol | Stanford University | P4 | BBB |
| Compound Edaravone | Nanfang Hospital, Southern Medical University | P4 | BBB |
| Argatroban | Second Affiliated Hospital, School of Medicine, Zhejiang University | P4 | BBB |
| 3-N-BUTYLPHTHALIDE | Nanfang Hospital, Southern Medical University | P4 | BBB |
| Tenecteplase | Hackensack Meridian Health | P4 | BBB |
| Prednisolone | University of California, San Francisco | P4 | BB |
| Clopidogrel | Nanfang Hospital, Southern Medical University | P4 | BB |
+42 more in the Ischemic Stroke cohort
Other indications for Aspirin
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Myocardial Infarction | — | P4 | A · 83 |
| Coronary Artery Disorder | — | P4 | BBB · 79 |
| Cardiovascular Disorder | — | P4 | BBB · 78 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Citation
Floatz Terminal. Aspirin in Ischemic Stroke. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 13, 2026. https://terminal.floatz.ai/assets/aspirin-ischemic-stroke-457
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