Aurora A Kinase Inhibitor Ly3295668
Head And Neck Neoplasm
Explore 23 assets in Head And Neck Neoplasm →Floatz Rating
CCC48/100
Confidence
Indicative
Sponsor
Eli Lilly and Company
Modality
Small molecule
Development Phase
Phase 1/2
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
37Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT03092934CT.gov A Study of AK-01 (LY3295668) in Solid Tumors | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
81High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Head And Neck Neoplasm
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Aurora A Kinase Inhibitor Ly3295668 (this asset) | Eli Lilly and Company | P1/2 | CCC · 48 |
| Cyclophosphamide | M.D. Anderson Cancer Center | P3 | B |
| Pembrolizumab | Mayo Clinic | P3 | B |
| Fluorouracilum | Rutgers, The State University of New Jersey | P4 | B |
| Pralsetinib, Trans- | Hoffmann-La Roche | P3 | B |
| Capecitabine | Rutgers, The State University of New Jersey | P4 | B |
| Cis-Diamminedichloroplatinum Ii | Hoffmann-La Roche | P3 | B |
| Nivolumab | Fred Hutchinson Cancer Center | P2 | CCC |
| Atezolizumab | University Medical Center Groningen | P2 | CCC |
+36 more in the Head And Neck Neoplasm cohort
Other indications for Aurora A Kinase Inhibitor Ly3295668
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Triple-Negative Breast Carcinoma | — | P1/2 | CCC · 50 |
| Non-Small Cell Lung Carcinoma | — | P1/2 | CCC · 48 |
| Small Cell Lung Carcinoma | — | P1/2 | CCC · 48 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Aurora A Kinase Inhibitor Ly3295668 in Head And Neck Neoplasm. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 14, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/aurora-a-kinase-inhibitor-ly3295668-head-and-neck-neoplasm
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