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Auto Cd34+Pbsc Transduced With A Lentiviral Vector Encoding A Novel Coagulation Factor Viii Transgene

Hemophilia A

Christian Medical College, Vellore, Indiagene_therapyPhase 1Active
CC
42/ 100
Provisional rating · Methodology v0.2

Rating breakdown

Clinical Evidence
32/ 100
Competitive Position
73/ 100

Competitive context

66 Active assets in the Hemophilia A cohort.

Asset / SponsorPhaseRating
Turoctocog Alfa
Novo Nordisk A/S
Phase 4A
Eptacog Alfa
AryoGen Pharmed Co.
Phase 4A
Rurioctocog Alfa Pegol
Takeda
Phase 4BBB
Turoctocog Alfa Pegol
Novo Nordisk A/S
Phase 3BBB
Immunoglobulin G4 [230-proline,de-449-lysine], anti-(human blood-coagulation factor IX)(human clone 0365-0001-9985 ?4-chain), disulfide with human clone 0365-0001-9985 ?-chain, (228?226?),(231?229?)-bis(disulfide) with anti-(human blood-coagulation factor X) immunoglobulin G4 [228-proline,405-leucine,409-lysine,de-447-lysine] (human clone 0365-0001-8174 ?4-chain) disulfide with human clone 0365-0001-8174 ?-chain
Novo Nordisk A/S
Phase 3BBB

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