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Autologous Anti-Cd19Car-4-1Bb-Cd3Zeta-Egfrt-Expressing Cd4+/Cd8+ Central Memory T-Lymphocytes Jcar014

Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements

Fred Hutchinson Cancer CenterCell therapyPhase 1Dormant
CC
41/ 100
Provisional rating · Methodology v0.2

Rating breakdown

Clinical Evidence
28/ 100
Competitive Position
81/ 100

Competitive context

25 Active assets in the Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements cohort.

Asset / SponsorPhaseRating
DEXAMETHASONE
National Cancer Institute (NCI)
Phase 2B
Cyclophosphamide
Mayo Clinic
Phase 2B
Ibrutinib
National Cancer Institute (NCI)
Phase 2B
IMMUNOGLOBULIN G 1 (HUMAN-MOUSE MONOCLONAL IDEC-C2B8 .GAMMA.1-CHAIN ANTI-HUMAN ANTIGEN CD 20), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL IDEC-C2B8 .KAPPA.-CHAIN, DIMER
Yazeed Sawalha
Phase 2B
Obinutuzumab
National Cancer Institute (NCI)
Phase 2CCC

View all 31 →

Same molecule, other indications

Autologous Anti-Cd19Car-4-1Bb-Cd3Zeta-Egfrt-Expressing Cd4+/Cd8+ Central Memory T-Lymphocytes Jcar014 is also rated in:

diffuse large B-cell lymphomaDormant
CC
Indicative ·
43 / 100
View asset →
primary mediastinal large B-cell lymphomaDormant
CC
Indicative ·
43 / 100
View asset →
relapsed/refractory diffuse large B-cell lymphomaDormant
C
Indicative ·
39 / 100
View asset →

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