Floatz Rating
CC47/100
Confidence
Indicative
Sponsor
Xencor, Inc.
Modality
monoclonal_antibody
Development Phase
Phase 1
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
32Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT03849469CT.gov A Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid Tumors | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Anal Squamous Cell Carcinoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Bavunalimab (this asset) | Xencor, Inc. | P1 | CC · 47 |
| Fluorouracilum | Columbia University | P2 | BB |
| Cis-Diamminedichloroplatinum Ii | Sixth Affiliated Hospital, Sun Yat-sen University | P3 | BB |
| Nivolumab | National Cancer Institute (NCI) | P3 | BB |
| Carboplatin | Fudan University | P3 | BB |
| Atezolizumab | Oncolytics Biotech | P2 | B |
| e7 tcr-t cells | Christian Hinrichs | P2 | B |
| Toripalimab | Sun Yat-sen University | P2 | B |
| Panitumumab | Grupo Espanol Multidisciplinario del Cancer Digestivo | P2 | B |
+31 more in the Anal Squamous Cell Carcinoma cohort
Other indications for Bavunalimab
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Non-Small Cell Lung Carcinoma | — | P1 | CC · 47 |
| Head And Neck Squamous Cell Carcinoma | — | P1 | CC · 47 |
| Squamous Cell Carcinoma Of Penis | — | P1 | CC · 47 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Bavunalimab in Anal Squamous Cell Carcinoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/bavunalimab-anal-squamous-cell-carcinoma
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