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Floatz Rating
CCC53/100
Confidence
Indicative
v0.2
Sponsor
Nationwide Children's Hospital
Modality
Small molecule
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Indicative
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
A Study of Cabozantinib as a Maintenance Agent to Prevent Progression or Recurrence in High-Risk Pediatric Solid Tumors
Recruiting

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
81High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Neuroblastoma

AssetSponsorPhaseRating
Cabozantinib (this asset)Nationwide Children's HospitalP2CCC · 53
EtoposideM.D. Anderson Cancer CenterP2/3BB
NivestimM.D. Anderson Cancer CenterP4BB
CyclophosphamideRobbie MajznerP2BB
CarboplatinSt. Jude Children's Research HospitalP2/3BB
Gm-CsfXinhua Hospital, Shanghai Jiao Tong University School of MedicineP4BB
MelphalanM.D. Anderson Cancer CenterP2/3BB
AdriamycinHoffmann-La RocheP2BB
IrinotecanMilton S. Hershey Medical CenterP2BB

+42 more in the Neuroblastoma cohort

Other indications for Cabozantinib

IndicationSponsorPhaseRating
Renal CarcinomaP4BB · 70
Castration-Resistant Prostate CarcinomaP3BB · 70
Kidney CancerP4BB · 66

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Cabozantinib in Neuroblastoma. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/cabozantinib-neuroblastoma

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