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Floatz Rating
CCC51/100
Confidence
Indicative
v0.2
Sponsor
National Cancer Institute (NCI)
Modality
Small molecule
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Moderate confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma
Recruiting
Codman Catheter/Synchromed Pump Hepatic Artery Chemotherapy for Unresectable Colorectal Metastases/Intrahepatic Cholangiocarcinoma
Terminated

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
73High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Colorectal Neoplasm

AssetSponsorPhaseRating
Dexasone (this asset)National Cancer Institute (NCI)P2CCC · 51
OxaliplatinPeking University Cancer Hospital & InstituteP4BBB
FluorouracilumRutgers, The State University of New JerseyP4BBB
Ferric Carboxymaltose [Ferinject]Nottingham University Hospitals NHS TrustP4BBB
IrinotecanShanghai Zhongshan HospitalP4BBB
CapecitabineRutgers, The State University of New JerseyP4BB
RegorafenibSergey Orlov, MDP4BB
NivolumabBristol-Myers SquibbP3BB
Ferric CationNottingham University Hospitals NHS TrustP4BB

+41 more in the Colorectal Neoplasm cohort

Other indications for Dexasone

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Dexasone in Colorectal Neoplasm. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/dexasone-colorectal-neoplasm

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