gamma1 heavy chain humanized (1-450) [VH (Homo sapiens IGHV1-46*02 (80.4%)-(IGHD) -IGHJ4*01 (100%), CDR-IMGT[8.8.14] (26-33.51-58.97-110)) (1-121)-Homo sapiens IGHG1*03, G1m3, nG1m1, G1v29 CH2 A84.4 (CH1 R120 (218) (122-219), hinge 1-15 (220-234), CH2 N84.4>A (301) (235-344), CH3 E12 (360), M14 (362) (345-449), CHS K2>del (450))(122-450)], (224-215')-disulfide with kappa light chain humanized (1'-215') [V-KAPPA (Homo sapiens IGKV3-20*01 (86.5%) -IGKJ1*01 (91.7%), CDR-IMGT [7.3.9](27-33.51-53.90-98)) (1'-108') -Homo sapiens IGKC*01(100%), Km3 A45.1 (154), V101 (192) (109'-215')], dimer (230-230'': 233-233'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV lacking the glutamine synthetase (GS-KO) gene, non-glycosylated
Diffuse Large B-cell Lymphoma
Rating breakdown
- Clinical Evidence
- 32/ 100
- Competitive Position
- 73/ 100
Competitive context
271 Active assets in the Diffuse Large B-cell Lymphoma cohort.
| Asset / Sponsor | Phase | Rating |
|---|---|---|
VINCRISTINE SULFATE National Cancer Institute (NCI) | Phase 2/3 | A |
Evomela Ruijin Hospital | Phase 4 | BBB |
Axicabtagene Ciloleucel Ruijin Hospital | Phase 4 | BBB |
PREDNISONE TABLETS Beth Israel Deaconess Medical Center | Phase 4 | BBB |
Inno-206 Beth Israel Deaconess Medical Center | Phase 4 | BBB |
View all 50 →
Same molecule, other indications
gamma1 heavy chain humanized (1-450) [VH (Homo sapiens IGHV1-46*02 (80.4%)-(IGHD) -IGHJ4*01 (100%), CDR-IMGT[8.8.14] (26-33.51-58.97-110)) (1-121)-Homo sapiens IGHG1*03, G1m3, nG1m1, G1v29 CH2 A84.4 (CH1 R120 (218) (122-219), hinge 1-15 (220-234), CH2 N84.4>A (301) (235-344), CH3 E12 (360), M14 (362) (345-449), CHS K2>del (450))(122-450)], (224-215')-disulfide with kappa light chain humanized (1'-215') [V-KAPPA (Homo sapiens IGKV3-20*01 (86.5%) -IGKJ1*01 (91.7%), CDR-IMGT [7.3.9](27-33.51-53.90-98)) (1'-108') -Homo sapiens IGKC*01(100%), Km3 A45.1 (154), V101 (192) (109'-215')], dimer (230-230'': 233-233'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV lacking the glutamine synthetase (GS-KO) gene, non-glycosylated is also rated in:
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