Gamma4 heavy chain Homo sapiens (1-446) [VH (Homo sapiens IGHV4-39*01 (96.0%) -(IGHD) -IGHJ3*02 (100%), CDR-IMGT [10.7.12] (26-35.53-59.98-109)) (1-120)-Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10, G4v4 CH2 A1.3, A1.2 (CH1 (121-218), hinge 1-12 S10>P (228) (219-230), CH2 F1.3>A (234), L1.2>A (235), L92 (309) (231-340), CH3 (341-445), CHS K2>del (446)) (121-446)], (134-215')-disulfide with kappa light chain Homo sapiens (1'-215') [V-KAPPA (Homo sapiens IGKV1-33*01 (96.8%) -IGKJ4*01 (100%), CDR-IMGT[6.3.10] (27'-32'.50'-52'.89'-98')) (1'-108') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (154'), V101 (192') (109'-215')], dimer (226-226'':229-229'')-bisdisulfide, produced in Chinese hamster ovary (CHO)-K1SV cell line lacking the glutamine synthetase gene (GS-KO), glycoform alfa
Non-small Cell Lung Cancer (NSCLC)
Rating breakdown
- Clinical Evidence
- 28/ 100
- Competitive Position
- 73/ 100
Competitive context
1205 Active assets in the Non-small Cell Lung Cancer (NSCLC) cohort.
| Asset / Sponsor | Phase | Rating |
|---|---|---|
Necitumumab Jonsson Comprehensive Cancer Center | Phase 3 | BBB |
Zorifertinib Alpha Biopharma (Jiangsu) Co., Ltd. | Phase 2/3 | BBB |
Glumetinib Shanghai JMT-Bio Inc. | Phase 3 | BBB |
d-0316 Betta Pharmaceuticals Co., Ltd. | Phase 2/3 | BBB |
Onartuzumab Hoffmann-La Roche | Phase 3 | BBB |
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Same molecule, other indications
Gamma4 heavy chain Homo sapiens (1-446) [VH (Homo sapiens IGHV4-39*01 (96.0%) -(IGHD) -IGHJ3*02 (100%), CDR-IMGT [10.7.12] (26-35.53-59.98-109)) (1-120)-Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10, G4v4 CH2 A1.3, A1.2 (CH1 (121-218), hinge 1-12 S10>P (228) (219-230), CH2 F1.3>A (234), L1.2>A (235), L92 (309) (231-340), CH3 (341-445), CHS K2>del (446)) (121-446)], (134-215')-disulfide with kappa light chain Homo sapiens (1'-215') [V-KAPPA (Homo sapiens IGKV1-33*01 (96.8%) -IGKJ4*01 (100%), CDR-IMGT[6.3.10] (27'-32'.50'-52'.89'-98')) (1'-108') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (154'), V101 (192') (109'-215')], dimer (226-226'':229-229'')-bisdisulfide, produced in Chinese hamster ovary (CHO)-K1SV cell line lacking the glutamine synthetase gene (GS-KO), glycoform alfa is also rated in:
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