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Homodimeric fragment crystallizable fusion protein comprised of the extracellular domain of the human transforming growth factor beta receptor type II linked to a human IgG1 Fc domain

Systemic Sclerosis

Merck Sharp & Dohme LLCprotein_peptidePhase 1Active
CC
47/ 100
Provisional rating · Methodology v0.2

Rating breakdown

Clinical Evidence
32/ 100
Competitive Position
95/ 100

Competitive context

24 Active assets in the Systemic Sclerosis cohort.

Asset / SponsorPhaseRating
Cyclophosphamide
Royal Brompton & Harefield NHS Foundation Trust
Phase 2/3BB
Iloprost
National Center for Research Resources (NCRR)
Phase 3BB
Bosentan
Actelion
Phase 3B
IMMUNOGLOBULIN G 1 (HUMAN-MOUSE MONOCLONAL IDEC-C2B8 .GAMMA.1-CHAIN ANTI-HUMAN ANTIGEN CD 20), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL IDEC-C2B8 .KAPPA.-CHAIN, DIMER
Royal Brompton & Harefield NHS Foundation Trust
Phase 2/3B
Anti-Thymoglobulin, Rabbit
Fred Hutchinson Cancer Center
Phase 2B

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