human hyaluronidase isozyme-5 (HYAL5, sperm adhesion molecule 1, SPAM1, hyaluronidase PH-20, EC:3.2.1.35) fragment (3-433, 1-431 in the current sequence) engineered variant with the structural domain replaced by the corresponding region of human hyaluronidase isozyme-1 (HYAL1)(<sup>306</sup>TLSIMRSMKSCLLDDNYMETI<sup>326</sup>><sup>304</sup>SWENTRTKESCQAIKEYMDTT<sup>324</sup>), produced in Chinese hamster ovary (CHO) cells, cell line DG44, glycoform alfa
Solid Tumors
Merck Sharp & Dohme LLCprotein_peptidePhase 3Active
CCC
52/ 100
Provisional rating · Methodology v0.2
Rating breakdown
- Clinical Evidence
- 45/ 100
- Competitive Position
- 65/ 100
Competitive context
207 Active assets in the Solid Tumors cohort.
| Asset / Sponsor | Phase | Rating |
|---|---|---|
FILGRASTIM Ankara Etlik City Hospital | Phase 2 | BB |
DEXAMETHASONE Hellenic Society of Hematology | Phase 3 | BB |
Carboplatin Bristol-Myers Squibb | Phase 3 | BB |
Ribociclib TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics) | Phase 4 | B |
CIS-DIAMMINEDICHLOROPLATINUM II Mabwell (Shanghai) Bioscience Co., Ltd. | Phase 3 | B |
View all 50 →
Same molecule, other indications
human hyaluronidase isozyme-5 (HYAL5, sperm adhesion molecule 1, SPAM1, hyaluronidase PH-20, EC:3.2.1.35) fragment (3-433, 1-431 in the current sequence) engineered variant with the structural domain replaced by the corresponding region of human hyaluronidase isozyme-1 (HYAL1)(<sup>306</sup>TLSIMRSMKSCLLDDNYMETI<sup>326</sup>><sup>304</sup>SWENTRTKESCQAIKEYMDTT<sup>324</sup>), produced in Chinese hamster ovary (CHO) cells, cell line DG44, glycoform alfa is also rated in:
Are you the sponsor?
Submit your data room for a Verified Rating. The public-data rating remains visible alongside.
Contact →