Idarubicin
Acute Myeloid Leukemia With Multilineage Dysplasia
Explore 33 assets in Acute Myeloid Leukemia With Multilineage Dysplasia →Floatz Rating
B57/100
Confidence
Indicative
Sponsor
University of Southern California
Modality
Small molecule
Development Phase
Phase 1/2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
44Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT03330821CT.gov Pevonedistat, Cytarabine, and Idarubicin in Treating Patients With Acute Myeloid Leukemia | — | Active Not Recruiting | — | — | — |
NCT02632708CT.gov Safety Study of AG-120 or AG-221 in Combination With Induction and Consolidation Therapy in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) With an IDH1 and/or IDH2 Mutation | — | Active Not Recruiting | — | — | — |
NCT00331513CT.gov Vorinostat and Idarubicin in Treating Patients With Relapsed or Refractory Leukemia or Myelodysplastic Syndromes | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Moderate confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Acute Myeloid Leukemia With Multilineage Dysplasia
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Idarubicin (this asset) | University of Southern California | P1/2 | B · 57 |
| Cytarabine | National Cancer Institute (NCI) | P3 | BB |
| Etoposide | Institut de Recherches Internationales Servier | P2 | BB |
| Decitabine | National Cancer Institute (NCI) | P3 | BB |
| Ivosidenib | Institut de Recherches Internationales Servier | P3 | BB |
| Cyclophosphamide | City of Hope Medical Center | P3 | BB |
| Fludarabine | National Cancer Institute (NCI) | P3 | BB |
| Busulfanum | National Cancer Institute (NCI) | P3 | BB |
| Cyclosporin A | Case Comprehensive Cancer Center | P3 | BB |
+41 more in the Acute Myeloid Leukemia With Multilineage Dysplasia cohort
Other indications for Idarubicin
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Acute Promyelocytic Leukemia | — | P4 | A · 81 |
| Acute Myeloid Leukemia With 11q23 Abnormalities | — | P2 | BBB · 76 |
| Adult Acute Lymphoblastic Leukemia | — | P4 | BBB · 76 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Idarubicin in Acute Myeloid Leukemia With Multilineage Dysplasia. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/idarubicin-acute-myeloid-leukemia-with-multilineage-dysplasia
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