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il13ralpha2-specific hinge-optimized 4-1bb-co-stimulatory car/truncated cd19-expressing autologous tn/mem cells

Recurrent WHO Grade II Glioma

City of Hope Medical CenterCell therapyPhase 1Active
CC
43/ 100
Provisional rating · Methodology v0.2

Rating breakdown

Clinical Evidence
28/ 100
Competitive Position
95/ 100

Competitive context

7 Active assets in the Recurrent WHO Grade II Glioma cohort.

Asset / SponsorPhaseRating
Pamiparib
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Phase 1/2B
Infigratinib
Helsinn Healthcare SA
Phase 1/2CC
Arm 4: Il13Ra2-Specific Car Tcm Cells
City of Hope Medical Center
Phase 1CC
Arm 2: Il13Ra2-Specific Car Tcm Cells
City of Hope Medical Center
Phase 1CC
Chlorotoxin -Cd28-Cd3Zeta-Cd19T-Expressing Car T-Lymphocytes
City of Hope Medical Center
Phase 1CC
Arm 3: Il13Ra2-Specific Car Tcm Cells
City of Hope Medical Center
Phase 1CC
Arm 1: Il13Ra2-Specific Car Tcm Cells
City of Hope Medical Center
Phase 1CC

Same molecule, other indications

il13ralpha2-specific hinge-optimized 4-1bb-co-stimulatory car/truncated cd19-expressing autologous tn/mem cells is also rated in:

cutaneous melanomaDormant
CC
Indicative ·
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paragangliomaDormant
CC
Indicative ·
43 / 100
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pheochromocytomaDormant
CC
Indicative ·
43 / 100
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