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IMMUNOGLOBULIN, ANTI-(HUMAN CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4) (HUMAN-MUS MUSCULUS MONOCLONAL XMAB22841 SINGLE-CHAIN VARIABLE FRAGMENT VH-LINKER-VL) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN .GAMMA.1-CHAIN C-REGION C-TERMINAL FRAGMENT), (257->230'),(260->233')-BIS(DISULFIDE) WITH IMMUNOGLOBULIN G1 ANTI-(HUMAN LYMPHOCYTE ACTIVATION GENE-3) (HUMAN-MUS MUSCULUS MONOCLONAL XMAB22841 .GAMMA.1-CHAIN) DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL XMAB22841 .KAPPA.-CHAIN

Triple Negative Breast Cancer

Xencor, Inc.monoclonal_antibodyPhase 1Dormant
CC
40/ 100
Provisional rating · Methodology v0.2

Rating breakdown

Clinical Evidence
32/ 100
Competitive Position
65/ 100

Competitive context

448 Active assets in the Triple Negative Breast Cancer cohort.

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Capivasertib
AstraZeneca
Phase 3BB
Cyclophosphamide
M.D. Anderson Cancer Center
Phase 4BB
Carboplatin
M.D. Anderson Cancer Center
Phase 4BB
Veliparib
National Cancer Institute (NCI)
Phase 3BB
Atezolizumab
European Institute of Oncology
Phase 3BB

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Same molecule, other indications

IMMUNOGLOBULIN, ANTI-(HUMAN CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4) (HUMAN-MUS MUSCULUS MONOCLONAL XMAB22841 SINGLE-CHAIN VARIABLE FRAGMENT VH-LINKER-VL) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN .GAMMA.1-CHAIN C-REGION C-TERMINAL FRAGMENT), (257->230'),(260->233')-BIS(DISULFIDE) WITH IMMUNOGLOBULIN G1 ANTI-(HUMAN LYMPHOCYTE ACTIVATION GENE-3) (HUMAN-MUS MUSCULUS MONOCLONAL XMAB22841 .GAMMA.1-CHAIN) DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL XMAB22841 .KAPPA.-CHAIN is also rated in:

head and neck squamous cell carcinomaDormant
CC
Indicative ·
47 / 100
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non-small cell lung carcinomaDormant
CC
Indicative ·
47 / 100
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anal squamous cell carcinomaDormant
CC
Indicative ·
47 / 100
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