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Immunoglobulin G1 [240-alanine,241-alanine], anti-(human folate receptor ?) (human monoclonal PRO1184 ?1-chain, complex with human monoclonal PRO1184 ?-chain, dimer, 214??,214???,226,226?,232,232?,235,235?-octakis(thioether) with N6-[39-[bis(1-deoxy-D-glucitol-1-yl)amino]-1-oxo-4,7,10,13,16,19,22,25,28,31,34,37-dodecaoxanonatriacont-1-yl]-N2-[6-(3-mercapto-2,5-dioxo-1-pyrrolidinyl)-1-oxohexyl]-L-lysyl-L-valyl-N5-(aminocarbonyl)-N-[4-[[[[[(1S,9S)-9-ethyl-5-fluoro-2,3,9,10,13,15-hexahydro-9-hydroxy-4-methyl-10,13-dioxo-1H,12H-benzo[de]pyrano[3?,4?:6,7]indolizino[1,2-b]quinolin-1-yl]amino]carbonyl]oxy]methyl]phenyl]-L-ornithinamide

Ovarian Cancer

Genmabantibody_drug_conjugatePhase 3Active
CCC
54/ 100
Provisional rating · Methodology v0.2

Rating breakdown

Clinical Evidence
52/ 100
Competitive Position
59/ 100

Competitive context

439 Active assets in the Ovarian Cancer cohort.

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Same molecule, other indications

Immunoglobulin G1 [240-alanine,241-alanine], anti-(human folate receptor ?) (human monoclonal PRO1184 ?1-chain, complex with human monoclonal PRO1184 ?-chain, dimer, 214??,214???,226,226?,232,232?,235,235?-octakis(thioether) with N6-[39-[bis(1-deoxy-D-glucitol-1-yl)amino]-1-oxo-4,7,10,13,16,19,22,25,28,31,34,37-dodecaoxanonatriacont-1-yl]-N2-[6-(3-mercapto-2,5-dioxo-1-pyrrolidinyl)-1-oxohexyl]-L-lysyl-L-valyl-N5-(aminocarbonyl)-N-[4-[[[[[(1S,9S)-9-ethyl-5-fluoro-2,3,9,10,13,15-hexahydro-9-hydroxy-4-methyl-10,13-dioxo-1H,12H-benzo[de]pyrano[3?,4?:6,7]indolizino[1,2-b]quinolin-1-yl]amino]carbonyl]oxy]methyl]phenyl]-L-ornithinamide is also rated in:

ovarian cancerDormant
B
Indicative ·
62 / 100
View asset →
Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer (NSCLC)Dormant
B
Indicative ·
60 / 100
View asset →
PSOCDormant
B
Indicative ·
60 / 100
View asset →

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