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Immunoglobulin G1 [de-C-terminal-lysine], anti-(human blood-coagulation factor III) (human monoclonal XB002 ?1-chain), disulfide with human monoclonal XB002 ?-chain, dimer, reduced, tetrakis(thioether) with N-[3-[2-[2-[2-(3-mercapto-2,5-dioxo-1-pyrrolidinyl)ethoxy]ethoxy]ethoxy]-1-oxopropyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(2R,3R)-3-[(2S)-1-[(3R,4S,5S)-4-[(N,N-dimethyl-L-valyl-L-valyl)methylamino]-3-methoxy-5-methyl-1-oxoheptyl]-2-pyrrolidinyl]-3-methoxy-2-methyl-1-oxopropyl]amino]sulfonyl]phenyl]-L-ornithinamide

Endometrial Cancer

Exelixisantibody_drug_conjugatePhase 1Dormant
CC
40/ 100
Provisional rating · Methodology v0.2

Rating breakdown

Clinical Evidence
32/ 100
Competitive Position
65/ 100

Competitive context

234 Active assets in the Endometrial Cancer cohort.

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Same molecule, other indications

Immunoglobulin G1 [de-C-terminal-lysine], anti-(human blood-coagulation factor III) (human monoclonal XB002 ?1-chain), disulfide with human monoclonal XB002 ?-chain, dimer, reduced, tetrakis(thioether) with N-[3-[2-[2-[2-(3-mercapto-2,5-dioxo-1-pyrrolidinyl)ethoxy]ethoxy]ethoxy]-1-oxopropyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(2R,3R)-3-[(2S)-1-[(3R,4S,5S)-4-[(N,N-dimethyl-L-valyl-L-valyl)methylamino]-3-methoxy-5-methyl-1-oxoheptyl]-2-pyrrolidinyl]-3-methoxy-2-methyl-1-oxopropyl]amino]sulfonyl]phenyl]-L-ornithinamide is also rated in:

esophageal squamous cell carcinomaDormant
CC
Indicative ·
47 / 100
View asset →
head and neck squamous cell carcinomaDormant
CC
Indicative ·
47 / 100
View asset →
Tissue Factor-Expressing Solid TumorsDormant
CC
Indicative ·
47 / 100
View asset →

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