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IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS CD37(TSPAN26, TETRASPANIN-26)), MUS MUSCULUS MONOCLONAL ANTIBODY; GAMMA1 HEAVY CHAIN (1-443) (MUS MUSCULUS VH (IGHV1S135*01 (96.90%)-(IGHD)-IGHJ4*01) (8.8.12) (1-119)-IGHG1*01 (CH1 E84>Q (177), P95>T (193), R96>W (194) (120-216), HINGE (217-229), CH2 (230-336), CH3 N84.2>D (395), N84.4>D (397) (337-441), CHS (442-443)) (120-443)), (221-214')-DISULFIDE WITH KAPPA LIGHT CHAIN (1'-214') (MUS MUSCULUS V-KAPPA (IGKV6-25*01 (93.70%)-IGKJ4*01) (6.3.9) (1'-107')-IGKC*01 (108'-214')); DIMER (223-223'':226-226'':228-228'')-TRISDISULFIDE

Refractory Diffuse Large B-Cell Lymphoma

Nordic Nanovectormonoclonal_antibodyPhase 1Dormant
CC
44/ 100
Provisional rating · Methodology v0.2

Rating breakdown

Clinical Evidence
32/ 100
Competitive Position
81/ 100

Competitive context

11 Active assets in the Refractory Diffuse Large B-Cell Lymphoma cohort.

Asset / SponsorPhaseRating
IMMUNOGLOBULIN G 1 (HUMAN-MOUSE MONOCLONAL IDEC-C2B8 .GAMMA.1-CHAIN ANTI-HUMAN ANTIGEN CD 20), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL IDEC-C2B8 .KAPPA.-CHAIN, DIMER
Sun Yat-sen University
Phase 3BBB
Ifosfamide
University of California, Davis
Phase 3BB
Ibrutinib
National Cancer Institute (NCI)
Phase 2BB
Carboplatin
University of California, Davis
Phase 3BB
Polatuzumab Vedotin
Ruijin Hospital
Phase 3BB

View all 16 →

Same molecule, other indications

IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS CD37(TSPAN26, TETRASPANIN-26)), MUS MUSCULUS MONOCLONAL ANTIBODY; GAMMA1 HEAVY CHAIN (1-443) (MUS MUSCULUS VH (IGHV1S135*01 (96.90%)-(IGHD)-IGHJ4*01) (8.8.12) (1-119)-IGHG1*01 (CH1 E84>Q (177), P95>T (193), R96>W (194) (120-216), HINGE (217-229), CH2 (230-336), CH3 N84.2>D (395), N84.4>D (397) (337-441), CHS (442-443)) (120-443)), (221-214')-DISULFIDE WITH KAPPA LIGHT CHAIN (1'-214') (MUS MUSCULUS V-KAPPA (IGKV6-25*01 (93.70%)-IGKJ4*01) (6.3.9) (1'-107')-IGKC*01 (108'-214')); DIMER (223-223'':226-226'':228-228'')-TRISDISULFIDE is also rated in:

non-Hodgkin lymphomaDormant
CCC
Indicative ·
55 / 100
View asset →
follicular lymphomaDormant
CCC
Indicative ·
53 / 100
View asset →

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