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Immunoglobulin G4 [237-proline,242-proline,243-valine,244-alanine,de-245-glycine], anti-(human mucin-16) (human monoclonal REGN5668 ?4-chain), disulfide with human monoclonal REGN5668 ?-chain, (235?228?),(238?231?)-bis(disulfide) with immunoglobulin G4 [230-proline,235-proline,236-valine,237-alanine,de-238-glycine,436-arginine,437-phenylalanine,446-proline] anti-(human CD28 antigen) (human monoclonal REGN5668 ?4-chain) disulfide with human monoclonal REGN5668 ?-chain

Ovarian Cancer

Regeneron Pharmaceuticalsmonoclonal_antibodyPhase 1/2Active
CC
40/ 100
Provisional rating · Methodology v0.2

Rating breakdown

Clinical Evidence
33/ 100
Competitive Position
59/ 100

Competitive context

524 Active assets in the Ovarian Cancer cohort.

Asset / SponsorPhaseRating
Tisotumab Vedotin
Seagen Inc.
Phase 2BB
TIL
Inge Marie Svane
Phase 2BB
Olaparib
Shandong University
Phase 4BB
Carboplatin
Fudan University
Phase 4BB
Irinotecan
ARCAGY/ GINECO GROUP
Phase 4BB

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Same molecule, other indications

Immunoglobulin G4 [237-proline,242-proline,243-valine,244-alanine,de-245-glycine], anti-(human mucin-16) (human monoclonal REGN5668 ?4-chain), disulfide with human monoclonal REGN5668 ?-chain, (235?228?),(238?231?)-bis(disulfide) with immunoglobulin G4 [230-proline,235-proline,236-valine,237-alanine,de-238-glycine,436-arginine,437-phenylalanine,446-proline] anti-(human CD28 antigen) (human monoclonal REGN5668 ?4-chain) disulfide with human monoclonal REGN5668 ?-chain is also rated in:

primary peritoneal carcinomaDormant
CC
Indicative ·
43 / 100
View asset →
fallopian tube cancerDormant
CC
Indicative ·
41 / 100
View asset →
endometrial carcinomaDormant
CC
Indicative ·
41 / 100
View asset →

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