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L-Valine, S-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenonyl-2-(aminomethyl)-4-thiazolecarbonyl-2-methylalanyl-, (5?2)-lactone, benzenesulfonate (1:1)

RAS Mutation

OnKure, Inc.Small moleculePhase 1/2Active
CCC
48/ 100
Provisional rating · Methodology v0.2

Rating breakdown

Clinical Evidence
37/ 100
Competitive Position
81/ 100

Competitive context

24 Active assets in the RAS Mutation cohort.

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Same molecule, other indications

L-Valine, S-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenonyl-2-(aminomethyl)-4-thiazolecarbonyl-2-methylalanyl-, (5?2)-lactone, benzenesulfonate (1:1) is also rated in:

NRAS Gene MutationDormant
CCC
Indicative ·
52 / 100
View asset →
melanomaDormant
CC
Indicative ·
44 / 100
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cancerDormant
C
Indicative ·
39 / 100
View asset →

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