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MUTATED HUMAN IMMUNOGLOBULIN G1 FC FRAGMENT ANTI-(HOMO SAPIENS IGG RECEPTOR FCRN LARGE SUBUNIT P51 (NEONATAL FC RECEPTORFCRN))(37-TYR(M>Y(32),39-THR(S>T(34),41-GLU(T>E(36),218-LYS(H>K(213)),219-PHE(N>F(214))(FC FRAGMENT OF HUMAN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 1)-(6-232)-PEPTIDE, DIMER (6-6':9-9')-BISDISULFIDE, PRODUCED IN CHO CELLS, GLYCOFORM ALFA

Optic Neuritis

Anastasia Vishnevetsky, MD, MPHprotein_peptidePhase 2Active
CCC
53/ 100
Provisional rating · Methodology v0.2

Rating breakdown

Clinical Evidence
38/ 100
Competitive Position
95/ 100

Competitive context

3 Active assets in the Optic Neuritis cohort.

Asset / SponsorPhaseRating
Interferon ?1 (human fibroblast protein moiety)
MidAmerica Neuroscience Research Foundation at Rowe Neurology Institute
Phase 4BB
Fampridine
Courtney Casserly
Phase 2/3BB
METHOTREXATE
MidAmerica Neuroscience Research Foundation at Rowe Neurology Institute
Phase 4BB
SIMVASTATIN
Glostrup University Hospital, Copenhagen
Phase 3B
PREDNISONE TABLETS
National Eye Institute (NEI)
Phase 3B

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