Floatz Rating
CC43/100
Confidence
Indicative
Sponsor
GRIN Therapeutics, Inc.
Modality
Small molecule
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
28Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06965881CT.gov Study to Evaluate the Pharmacokinetics and Safety Effects Following Coadministration of Carbamazepine or Itraconazole With Radiprodil in Healthy Adults | — | Terminated | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Isolated Focal Cortical Dysplasia
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Neurotop (this asset) | GRIN Therapeutics, Inc. | P1 | CC · 43 |
| Everolimus | NYU Langone Health | P2 | B |
| Radiprodil | GRIN Therapeutics, Inc. | P1/2 | CCC |
| svg103 | Sovargen | P1/2 | CCC |
| Itraconazole | GRIN Therapeutics, Inc. | P1 | CC |
| Blood, Whole | King's College Hospital NHS Trust | N/A | D |
Other indications for Neurotop
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Epilepsy | — | P4 | BBB · 74 |
| Focal Epilepsy | — | P4 | BBB · 74 |
| Bipolar Disorder | — | P4 | BBB · 72 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Neurotop in Isolated Focal Cortical Dysplasia. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/neurotop-isolated-focal-cortical-dysplasia
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