Floatz Rating
CCC52/100
Confidence
Indicative
Sponsor
First People's Hospital of Hangzhou
Modality
Small molecule
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Indicative
Detailed axis rationale is planned and will be published soon.
No trial-level evidence is linked to this axis yet.
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Hand-Foot Syndrome
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Niacin (this asset) | First People's Hospital of Hangzhou | P2 | CCC · 52 |
| Adriamycin | Swiss Cancer Institute | P3 | BB |
| Mecobalamin | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | P3 | B |
| Celecoxib | Affiliated Hospital of Qinghai University | P3 | B |
| Tazarotene | Dana-Farber Cancer Institute | P2 | CCC |
| Indometacinum | National Taiwan University Hospital | P2 | CCC |
| Nicotine | University of California, San Francisco | P2 | CCC |
| 0.1% uracil cream | Nanometics (d.b.a. PHD Biosciences) | P1/2 | CCC |
| Clobetasol Propionate 0.05% Cream | Gazi University | N/A | D |
+3 more in the Hand-Foot Syndrome cohort
Other indications for Niacin
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Abdominal Obesity-Metabolic Syndrome | — | P4 | BB · 68 |
| Inherited Lipid Metabolism Disorder | — | P4 | BB · 68 |
| Coronary Artery Disorder | — | P4 | BB · 68 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Niacin in Hand-Foot Syndrome. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 13, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/niacin-hand-foot-syndrome
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