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OLESOXIME, E-

Spinal Muscular Atrophy Type II

Hoffmann-La RocheSmall moleculePhase 2Dormant
B
57/ 100
Provisional rating · Methodology v0.2

Rating breakdown

Clinical Evidence
42/ 100
Competitive Position
95/ 100

Competitive context

7 Active assets in the Spinal Muscular Atrophy Type II cohort.

Asset / SponsorPhaseRating
Srk-015
Scholar Rock, Inc.
Phase 3BB
NON-REPLICATING RECOMBINANT SELF-COMPLEMENTARY (SC) ADENO-ASSOCIATED VIRUS SEROTYPE 9 (AAV9) VECTOR CONTAINING THE CDNA OF THE SURVIVAL OF MOTOR NEURON 2 (SMN2) GENE UNDER THE CONTROL OF THE HYBRID CYTOMEGALOVIRUS (CMV) ENHANCER/CHICKEN BETA-ACTIN PROMOTER (CBA)
Novartis Gene Therapies
Phase 3B
Risdiplam
Scholar Rock, Inc.
Phase 2CCC
Nusinersen
Scholar Rock, Inc.
Phase 2CCC
Sodium Phenylbutyrate
Westat
Phase 1/2CCC
gc101
GeneCradle Inc
Phase 1/2CCC
Gcb-001
Genecombio Ltd.
N/AD
oav101
Novartis Pharmaceuticals
Phase 3NR

Same molecule, other indications

OLESOXIME, E- is also rated in:

spinal muscular atrophy, type IIIDormant
B
Indicative ·
57 / 100
View asset →
spinal muscular atrophyDormant
B
Indicative ·
57 / 100
View asset →
amyotrophic lateral sclerosisDormant
B
Indicative ·
57 / 100
View asset →

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