Oncolytic Virus Rp1
Cutaneous Neuroendocrine Carcinoma
Explore 45 assets in Cutaneous Neuroendocrine Carcinoma →Floatz Rating
CC45/100
Confidence
Indicative
Sponsor
Replimune, Inc.
Modality
gene_therapy
Development Phase
Phase 1/2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
33Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT04349436CT.gov Study to Investigate the Efficacy and Safety of RP1 in Adult Patients With Organ Transplants and Advanced Skin Malignancies | — | Active Not Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
81High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Cutaneous Neuroendocrine Carcinoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Oncolytic Virus Rp1 (this asset) | Replimune, Inc. | P1/2 | CC · 45 |
| Pembrolizumab | Merck Sharp & Dohme LLC | P3 | BB |
| Cyclophosphamide | Merck Sharp & Dohme LLC | P2/3 | BB |
| Atezolizumab | Ariceum Therapeutics GmbH | P2 | B |
| Fludarabine | Sotio Biotech Inc. | P2 | B |
| Durvalumab | Ariceum Therapeutics GmbH | P2 | B |
| Ifx-Hu2.0 | TuHURA Biosciences, Inc. | P2/3 | B |
| Nivolumab | Fred Hutchinson Cancer Center | P2 | B |
| ICP34.5-, ICP47-DELETED HERPES SIMPLEX VIRUS 1 (HSV-1) INCORPORATING THE HUMAN GM-CSF GENE | University of Zurich | P2 | B |
+42 more in the Cutaneous Neuroendocrine Carcinoma cohort
Other indications for Oncolytic Virus Rp1
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Melanoma | — | P3 | B · 58 |
| Skin Carcinoma | — | P2 | CCC · 53 |
| Cutaneous Melanoma | — | P2 | CCC · 53 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Oncolytic Virus Rp1 in Cutaneous Neuroendocrine Carcinoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/oncolytic-virus-rp1-cutaneous-neuroendocrine-carcinoma
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