Ponatinib

KRAS Gene Mutation

Memorial Sloan Kettering Cancer CenterSmall moleculePhase 1/2Dormant

CCC

52/ 100

Provisional rating · Methodology v0.2

Rating breakdown

Clinical Evidence: 37/ 100
Competitive Position: 95/ 100

Competitive context

13 Active assets in the KRAS Gene Mutation cohort.

Asset / Sponsor	Phase	Rating
gsk1120212 Memorial Sloan Kettering Cancer Center	Phase 2	BB
METHOTREXATE Stanford University	Phase 2	B
5-azacytidine Stanford University	Phase 2	B
Palbociclib Calithera Biosciences, Inc	Phase 1/2	B
Regorafenib Stanford University	Phase 2	B

View all 30 →

Same molecule, other indications

Ponatinib is also rated in:

chronic myeloid leukemiaDormant

BB

Indicative ·

66 / 100

B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)Dormant

BB

Indicative ·

65 / 100

blast phase chronic myelogenous leukemia, BCR-ABL1 positiveDormant

BB

Indicative ·

65 / 100

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