Quetiapine
Substance Dependence
Floatz Rating
B63/100
Confidence
Indicative
Sponsor
Creighton University
Modality
Small molecule
Development Phase
Phase 4 / Approved
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
53Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT00208143CT.gov Seroquel Therapy for Substance Use Disorders Comorbid With Schizophrenia | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Indicative
Detailed axis rationale is planned and will be published soon.
Same indication · Substance Dependence
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Quetiapine (this asset) | Creighton University | Approved | B · 63 |
| Valproic Acid | Creighton University | P4 | B |
| Ascrinvacumab | Suzhou Kintor Pharmaceutical Inc, | P1/2 | CCC |
| Nivolumab | Suzhou Kintor Pharmaceutical Inc, | P1/2 | CCC |
| Citicoline | Deborah Yurgelun-Todd | N/A | D |
| Risperidone | Tel-Aviv Sourasky Medical Center | P4 | NR |
| gsk598809 capsules | GlaxoSmithKline | P1 | NR |
Other indications for Quetiapine
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Schizoaffective Disorder | — | P4 | BBB · 76 |
| Bipolar Disorder | — | P4 | BBB · 74 |
| Substance Abuse | — | P4 | BBB · 74 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Quetiapine in Substance Dependence. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 14, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/quetiapine-substance-dependence
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