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Spk-8016

Factor VIII (FVIII)

Spark Therapeutics, Inc.gene_therapyPhase 1/2Dormant
CCC
52/ 100
Provisional rating · Methodology v0.2

Rating breakdown

Clinical Evidence
37/ 100
Competitive Position
95/ 100

Competitive context

67 Active assets in the Factor VIII (FVIII) cohort.

Asset / SponsorPhaseRating
Turoctocog Alfa
Novo Nordisk A/S
Phase 4A
Eptacog Alfa
AryoGen Pharmed Co.
Phase 4A
Rurioctocog Alfa Pegol
Takeda
Phase 4BBB
bay94-9027
Bayer
Phase 4BBB
Immunoglobulin G4 [230-proline,de-449-lysine], anti-(human blood-coagulation factor IX)(human clone 0365-0001-9985 ?4-chain), disulfide with human clone 0365-0001-9985 ?-chain, (228?226?),(231?229?)-bis(disulfide) with anti-(human blood-coagulation factor X) immunoglobulin G4 [228-proline,405-leucine,409-lysine,de-447-lysine] (human clone 0365-0001-8174 ?4-chain) disulfide with human clone 0365-0001-8174 ?-chain
Novo Nordisk A/S
Phase 3BBB

View all 50 →

Same molecule, other indications

Spk-8016 is also rated in:

blood coagulation diseaseDormant
CCC
Indicative ·
52 / 100
View asset →
inherited blood coagulation disorderDormant
CCC
Indicative ·
52 / 100
View asset →
disease of genetic or genomic mechanismDormant
CCC
Indicative ·
52 / 100
View asset →

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