Floatz Rating
B62/100
Confidence
Indicative
Sponsor
US Department of Veterans Affairs
Modality
Small molecule
Development Phase
Phase 3
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
49Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT00108589CT.gov S-Adenosylmethionine Therapy for Non-Alcoholic Steatohepatitis | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Hepatitis
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| S,S-Adenosylmethionine (this asset) | US Department of Veterans Affairs | P3 | B · 62 |
| Midazolam | Erasme University Hospital | P4 | BB |
| Meperidine | Erasme University Hospital | P4 | BB |
| Orlistat | St. Louis University | P4 | BB |
| Entecavir | Cttq | P4 | BB |
| Total Glucosides Of Paeony | West China Hospital | P4 | BB |
| Magnesium Isoglycyrrhizinate | Cttq | P4 | BB |
| Diammonium Glycyrrhizinate | Cttq | P4 | BB |
| Ursodeoxycholic Acid | West China Hospital | P4 | BB |
+23 more in the Hepatitis cohort
Other indications for S,S-Adenosylmethionine
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Depressive Disorder | — | P2/3 | B · 63 |
| Cirrhosis Of Liver | — | P2 | CCC · 53 |
| Metabolic Dysfunction-Associated Steatotic Liver Disease | — | P2 | CCC · 53 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. S,S-Adenosylmethionine in Hepatitis. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/ss-adenosylmethionine-hepatitis
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