247 assets in Acute Lymphoblastic Leukemia

Lapine T-Lymphocyte Immune Globulin

New Donor-Derived Cd7 Car T-Cell

Prior-Hsct Donor-Derived Cd7 Car T-Cell

Rimiducid

19-28z/il-18 car t cells

28137 T cells

Anti-Interleukin-7 Receptor ? Monoclonal Antibody

Cart22-65S Cells

cd19car-28-zeta t cells

cd19car-cd28-cd3zeta-egfrt-expressing tcm-enriched t-lymphocytes

cd19car-cd28-cd3zeta-egfrt-expressing tn/mem-enriched t-lymphocytes

cd19cat-41bbz car t-cells

cd8+ and cd4+ donor memory t-cells-expressing ha1-specific tcr

Cetuximab

Duvelisib

Egfrt/19-28Z/Il-12 Car T-Lymphocytes

Exercise Mobilized Prophylactic Dli

Fctx-Cl19-1

Hpc-A

Lcar-Aio Cells

Mb-Cart19.1

Ratg

Ribociclib

Tagraxofusp

Tcr Transduced T-Cells

cta101

Dordaviprone

Tozinameran

Asciminib

Autologous Hucd19 Car T Cells

Autologous T Cells Obtained From Peripheral Blood Mononuclear Cells By Leukapheresis, Transduced With A Self-Inactivating, Nonreplicating Lentiviral Vector, Encoding A T Cell Chimeric Antigen Receptor Targeting Cd19. The Expressed Transgene Comprises A Cd8? Leader Sequence, A Murine Anti-Cd19 Single Chain Variable Fragment (Scfv) Derived From The Mouse Hybridoma Fmc63, A Cd8? Hinge And Transmembrane Region, And A 4-1Bb (Cd137) And Cd3? (Tcr?) Signaling Domain And Is Under Control Of The Elongation Factor 1 Alpha (Ef1?) Promoter. The Construct Is Flanked By 5' And 3' Long Terminal Repeats (Ltrs) And Also Contains A ? Packaging Signal, A Rev Response Element (Rre), A Central Polypurine Tract (Cppt) Sequence And An Optimized Woodchuck Hepatitis Virus Posttranscriptional Regulatory Element (Wpre). The Leukapheresis Material Is Enriched For Cd4/Cd8 T Cells By Positive Immunoselection, Activated By Cd3 And Cd28 Agonists And Transduced With The Vector. Without Further Cell Propagation, The T Cells Are Washed, Formulated For Infusion, And Cryopreserved. The Substance Is Composed Of ?80% T Cells And ?1% B Cells, With A Mixture Of Transgene Positive (>3.4%) And Negative T Cells. The Cd4+ And Cd8+ Naïve T Cell Subsets (Cd45Ra+Ccr7+) Present In The Leukapheresis Material Are Largely Retained

Capivasertib

cd19-car_lenti t cell

Chimeric Antigen Receptor Modified T Cells Infusion

Clic-1901

Cobicistat

Cytokine-Treated Veto Cells

Ex-Vivo Expanded Γδ T Cell Infusion

Itraconazole

kq-2002 car-t cells 〈cd19/cd22 car t-cells〉

mc-1-50

Mezigdomide

Midazolam

mk-1045

Ziftomenib

Bpx-501 T Cells

Car-Nk-Cd19 Cells

Prgn-3007

Bcma Targeted Car T-Cells

cd19 specific chimeric antigen receptor t cell