50 assets in Anaplastic Large Cell Lymphoma

Crizotinib

Adriamycin

Brentuximab Vedotin

Cyclophosphamide

Etoposide

Dexasone

Fludarabine

Nivestim

Cyclosporin A

Methotrexate

Romidepsin

Lenalidomide

Prednisone

Alectinib

Vinorelbine Ditartrate

Pralatrexate

Nivolumab

Entrectinib

ICP34.5-, ICP47-DELETED HERPES SIMPLEX VIRUS 1 (HSV-1) INCORPORATING THE HUMAN GM-CSF GENE

Treosulfan

azd3470

Pembrolizumab

Parsaclisib

Anti-Cd7 Car-T Cells

Azacitidine

Anti-Cd30 Bispecific Antibody-Armed Anti-Cd3-Activated Autologous T-Cells

Autologous T Cells Obtained From Peripheral Blood Mononuclear Cells By Leukapheresis, Transduced With A Self-Inactivating, Nonreplicating Lentiviral Vector, Encoding A T Cell Chimeric Antigen Receptor Targeting Cd19. The Expressed Transgene Comprises A Cd8? Leader Sequence, A Murine Anti-Cd19 Single Chain Variable Fragment (Scfv) Derived From The Mouse Hybridoma Fmc63, A Cd8? Hinge And Transmembrane Region, And A 4-1Bb (Cd137) And Cd3? (Tcr?) Signaling Domain And Is Under Control Of The Elongation Factor 1 Alpha (Ef1?) Promoter. The Construct Is Flanked By 5' And 3' Long Terminal Repeats (Ltrs) And Also Contains A ? Packaging Signal, A Rev Response Element (Rre), A Central Polypurine Tract (Cppt) Sequence And An Optimized Woodchuck Hepatitis Virus Posttranscriptional Regulatory Element (Wpre). The Leukapheresis Material Is Enriched For Cd4/Cd8 T Cells By Positive Immunoselection, Activated By Cd3 And Cd28 Agonists And Transduced With The Vector. Without Further Cell Propagation, The T Cells Are Washed, Formulated For Infusion, And Cryopreserved. The Substance Is Composed Of ?80% T Cells And ?1% B Cells, With A Mixture Of Transgene Positive (>3.4%) And Negative T Cells. The Cd4+ And Cd8+ Naïve T Cell Subsets (Cd45Ra+Ccr7+) Present In The Leukapheresis Material Are Largely Retained

c7r.cd30.car-ebvst cells

Gm-Csf

nkx019

PF-08046044

pf-08046045

Sgn-35

Abatacept Recombinant

Autologous Ccr4 Car T Cells

cd30.car-t

Duvelisib

Immunoglobulin G4, Anti-(Human Programmed Cell Death Protein 1) (Human Monoclonal Regn2810 Heavy Chain), Disulfide With Human Monoclonal Regn2810 .Kappa.-Chain, Dimer

Lcar-Hl30 Cells

Recombinant Vesicular Stomatitis Virus-Expressing Interferon-Beta

Ruxolitinib

Wu-Cart-007

Anti Cd30 Car-T Cell

Bexarotene

Kenacort

Nitrogen Mustard