1,125 assets in Non-Small Cell Lung Carcinoma

Dabigatran Etexilate

e-602

Esomeprazole

Neurotop

[111in]-fpi-2107

177Lu-DOTA-ABM-5G

[68Ga]Ga DOTA-5G

Abbv-637

Absk043

Absk061

Alpha Tocopherol

Amg 794

asp5834

ast2303 tablets 。

Autologous Cd3+ Enriched T Lymphocytes Obtained From Peripheral Blood Mononuclear Cells (Pbmcs) By Apheresis. The Cells Are Transduced With A Self-Inactivating, Non-Replicating Lentiviral Vector Encoding An Enhanced-Affinity T Cell Receptor (Tcr) Targeting The Hla-A*02:01-Restricted Mage-A4 Peptide (Gvydgrehtv) Alongside The Cd8 Alpha (Cd8?) Co-Receptor. The Expressed Transgene Comprises The Coding Sequence For The Cd8? Co-Receptor, Separated By A Foot-And-Mouth Disease Virus 2A Self-Cleaving Peptide Sequence From The Coding Sequence Of The Mage-A4 T-Cell Receptor Alpha And Beta Chains That Are Separated From Each Other By A Porcine Teschovirus-1 2A Self-Cleaving Peptide Sequence, Under Control Of The Human Elongation Factor 1 Alpha (Ef-1?) Promoter. The Construct Is Flanked By 5' And 3' Long Terminal Repeats (Ltrs) And Also Contains A Trna Primer Binding Site, A ? Packaging Signal, A Truncated Gag, A Rev Response Element (Rre) And A Central Polypurine Tract (Cppt) Sequence 5' To The Transgene, And A Polypurine Tract (Ppt) 3' To The Transgene. The Vector Is Pseudotyped With The Vesicular Stomatitis Virus (Vsv) G Envelope Glycoprotein. The Cd3+ T Lymphocytes Are Purified And Activated Using Anti-Cd3/Anti-Cd28 Monoclonal Antibody Coated Magnetic Beads. The Cells Are Then Cultured In Media Containing Interleukin 2 (Il-2), Human Ab Serum And A Protein Kinase B (Akt Inhibitor). The Cells Are Cd3+ (> 80%), Express The High Affinity Mage-A4 Specific Tcr And Cd8? Co-Receptor (Cd8? +Tcr+; >16%) And Are Cytotoxic To Mage-A4 Expressing Tumor Cells

Azacytidine

Aztreonam

bc008-1a

Bgb-53038

Biological Ni-1801

Bms-986523

Bojungikki-Tang

bp-102

Bpi-572270

ca9hu-1

Chadox1-Magea3-Nyeso

Cromoglicic Acid

C-Til051

Darlifarnib

Dpx-Survivac

Dual-Target Antigen-Selected Car-Nk

Eb-Select Single-Target Car-Nk Cells

Elimusertib

Elvn-002

es102

f520

Fam-Trastuzumab Deruxtecan-Nxki

Febuxostat

Fermented Wheat Germ Extract

fl-101

Fpi-2053

Gamma1 Heavy Chain Humanized (1-448) [Vh (Homo Sapiens Ighv3-15*07 (86.9%)--(Ighd) -Ighj1*01(90.9%), Cdr-Imgt [8.10.9] (26-33.51-60.99-107))(1-118) -Homo Sapiens Ighg1*01 (100%), G1M17,1 Ch1K120, Ch3 D12, L14 (Ch1 K120 (215) (119-216),Hinge 1-15 (217-231), Ch2 (232-341), Ch3 D12 (357), L14 (359) (342-446), Chs (447-448)) (119-448)], (221-220')-Disulfide With Kappa Light Chain Humanized (1'-220') [V-Kappa (Homo Sapiens Igkv2-24*01 (90.0%)-Igkj2*01 (100%), Cdr-Imgt [11.3.10] (27-37.55-57.94-103)) (1'-113') -Homo Sapiens Igkc*01 (100%), Km3, A45.1 (159), V101 (197) (114'-220')]; Dimer (227-227'':230-230'')-Bisdisulfide, Produced In Chinese Hamster Ovary (Cho) Cells, Derived From The Cell Line Cho-K1, Glycoform Alfa

gen1042

gi-108

Giloralimab

Gtaexs617

Gumarontinib

Herombopag Olamine Tablets

hs-10504

Hwk-007