513 assets in Ovarian Cancer

Axitinib

Azenosertib

b013

Bendamustine

Bicalutamide

Binimetinib

Brimonidine

Cbx-12

Cilastatine

Dat-2645

Diphtheria Toxoid

Diphtheria Toxoid Adsorbed

Exemestane

Fruquintinib

Gemogenovatucel-T

Goserelin

Imgn151

Immunoglobulin G1, Anti-(Human Vascular Endothelial Growth Factor Receptor Type Vegfr-2 Extracellular Domain) (Human Monoclonal Imc-1121B .Gamma.-Chain), Disulphide With Human Monoclonal Imc-1121B .Kappa.-Chain, Dimer

Lorigerlimab

Losartan

Memory Cytokine-Enhanced Nk Cells

Mirvetuximab Soravtansine-Gynx

ose2101

Osimertinib

Prednisolone

Senaparib

Surufatinib

Tetanus Toxoid

Thiosulfate Ion(2-)

Trastuzumab Emtansine

Tuvonralimab

Vismodegib

Young Til

Adavosertib

Avelumab

Cobimetinib

esg401

Itraconazole

Mirabegron

Oregovamab

Zoledronate

Abemaciclib

Apsolol

Atorvastatin

Autologous Cd3+ Enriched T Lymphocytes Obtained From Peripheral Blood Mononuclear Cells (Pbmcs) By Apheresis. The Cells Are Transduced With A Self-Inactivating, Non-Replicating Lentiviral Vector Encoding An Enhanced-Affinity T Cell Receptor (Tcr) Targeting The Hla-A*02:01-Restricted Mage-A4 Peptide (Gvydgrehtv) Alongside The Cd8 Alpha (Cd8?) Co-Receptor. The Expressed Transgene Comprises The Coding Sequence For The Cd8? Co-Receptor, Separated By A Foot-And-Mouth Disease Virus 2A Self-Cleaving Peptide Sequence From The Coding Sequence Of The Mage-A4 T-Cell Receptor Alpha And Beta Chains That Are Separated From Each Other By A Porcine Teschovirus-1 2A Self-Cleaving Peptide Sequence, Under Control Of The Human Elongation Factor 1 Alpha (Ef-1?) Promoter. The Construct Is Flanked By 5' And 3' Long Terminal Repeats (Ltrs) And Also Contains A Trna Primer Binding Site, A ? Packaging Signal, A Truncated Gag, A Rev Response Element (Rre) And A Central Polypurine Tract (Cppt) Sequence 5' To The Transgene, And A Polypurine Tract (Ppt) 3' To The Transgene. The Vector Is Pseudotyped With The Vesicular Stomatitis Virus (Vsv) G Envelope Glycoprotein. The Cd3+ T Lymphocytes Are Purified And Activated Using Anti-Cd3/Anti-Cd28 Monoclonal Antibody Coated Magnetic Beads. The Cells Are Then Cultured In Media Containing Interleukin 2 (Il-2), Human Ab Serum And A Protein Kinase B (Akt Inhibitor). The Cells Are Cd3+ (> 80%), Express The High Affinity Mage-A4 Specific Tcr And Cd8? Co-Receptor (Cd8? +Tcr+; >16%) And Are Cytotoxic To Mage-A4 Expressing Tumor Cells

Avutometinib

Bet Bromodomain Inhibitor Zen-3694

Cmp 001

Datopotamab Deruxtecan

Dpx-Survivac