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Therapeutic Asset Ratings

1,179 results matching 1 filter

91,583 assets · 7,906 sponsors · 3,128 indications
Methodology v0.2
AssetSponsorPhaseRating
Sotigalimab
Colorectal Cancer
M.D. Anderson Cancer CenterP1CC (42)
Sotigalimab
Malignant Pancreatic Neoplasm
M.D. Anderson Cancer CenterP1CC (42)
Dordaviprone
Acute Lymphoblastic Leukemia
M.D. Anderson Cancer CenterP1/2CC (42)
Utomilumab
Castration-Resistant Prostate Carcinoma
M.D. Anderson Cancer CenterP1/2CC (42)
Utomilumab
Metastatic Malignant Neoplasm
M.D. Anderson Cancer CenterP1/2CC (42)
Magrolimab
B-Cell Non-Hodgkin Lymphoma
M.D. Anderson Cancer CenterP2CC (41)
allogeneic natural killer (NK) cells isolated from peripheral blood leukapheresis of individual donors. The cells are co-cultured in media containing interleukin 15 (IL-15) and nicotinamide (NAM, niacinamide) with expansion enhanced by the presence of feeder cells. The final cell population consists of 97-99% CD3-CD56+ NK cells, with >10% expressing CD16 (also known as Fc?RIII) and CD62L (also known as L-selectin) and with capacity to degranulate (surface expression of CD107? [Lysosome-associated membrane glycoprotein 1]; >10%), and to kill target cells (>10%) in co-culture assays against human cancer cell lines.
Glioblastoma
M.D. Anderson Cancer CenterP1CC (41)
Alpelisib
Cutaneous Melanoma
M.D. Anderson Cancer CenterP1CC (41)
Anti-Pr1/Hla-A2 Monoclonal Antibody Hu8F4
Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome
M.D. Anderson Cancer CenterP1CC (41)
Cabozantinib
Breast Carcinoma
M.D. Anderson Cancer CenterP1CC (41)
Capivasertib
Fallopian Tube Carcinoma
M.D. Anderson Cancer CenterP1CC (41)
Capivasertib
Primary Peritoneal Carcinoma
M.D. Anderson Cancer CenterP1CC (41)
Edetate Calcium Disodium
Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome
M.D. Anderson Cancer CenterP1CC (41)
G 207
Brain Disorder
M.D. Anderson Cancer CenterP1CC (41)
Imiquimod
Colorectal Adenocarcinoma
M.D. Anderson Cancer CenterP1CC (41)
Imiquimod
Pancreatic Ductal Adenocarcinoma
M.D. Anderson Cancer CenterP1CC (41)
Immunoglobulin G1 [de-236-glycine,267-glutamic acid,de-C-terminal lysine], anti-(human tumor necrosis factor receptor TNFRSF9) (human-Mus musculus monoclonal LVGN6051 ?1-chain), disulfide with human-Mus musculus monoclonal LVGN6051 ?-chain, dimer
Uveal Melanoma
M.D. Anderson Cancer CenterP1CC (41)
Immunoglobulin G1 [de-236-glycine,de-C-terminal lysine], anti-(human CD40 antigen) (human monoclonal LVGN7409 ?1-chain), disulfide with human monoclonal LVGN7409 ?-chain, dimer
Uveal Melanoma
M.D. Anderson Cancer CenterP1CC (41)
Ipilimumab
Richter Transformation
M.D. Anderson Cancer CenterP1CC (41)
IPN 60090
Cutaneous Melanoma
M.D. Anderson Cancer CenterP1CC (41)
Oncolytic Adenovirus Ad5-Dnx-2401
Glioblastoma
M.D. Anderson Cancer CenterP1CC (41)
Pradusinstobart
Uveal Melanoma
M.D. Anderson Cancer CenterP1CC (41)
sar445877
Colorectal Cancer
M.D. Anderson Cancer CenterP1CC (41)
Sti-6129
Acute Myeloid Leukemia
M.D. Anderson Cancer CenterP1CC (41)
Succimer
Myeloproliferative Neoplasm
M.D. Anderson Cancer CenterP1CC (41)
Showing 1026 to 1050 of 1,179 assets
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